If you're using a SERT, that means you've got narrow-band O2 sensors (if any at all, depending on model year). The Pro Tuner will do nothing for you in the open-loop areas unless it's got its own wide-band O2 sensors. Wherever there is no O2 feedback available, separate exhaust gas analysis will be required to tune the engine. Either this can be done with something like the Daytona-Sensors.com twin-scan II while riding/logging, or on a dyno. If it isn't done, you're just rolling the dice.