The difference between a stock Sportster saddle and a Harley pillow top is a difference of at least 10x in comfortable mileage for me.

 

I put Mustang seats on my Sportster and Roadglide. Before I got into RG's I regularly did 300-600 mile days on the Sportster (2000 1200C w/ Progressive front and rear suspension). A good seat makes all the difference in the world. If you plan on touring get a good seat!

 

Hubby has a Mustang on his 2005 Dyna Wide Glide Makes the world of difference on this bike.
I still have the stock seat on my 2007 Heritage Soft tail Classic. I have very little problems with it.
On both bikes if we are going on long trips over 300 then we will be using our gel seat pads. That helps

 

A seat can make all the difference in the world as you are sitting on it while on the bike. We reshaped a seat and it is so much more comfortable. Electric carving knife works great and a little extra padding depending on the kind of seat you have.

 

Huge difference and another vote here for Mustang.

 

Mustang seats are excellent. You won't be sorry for making the change. My 06 Low Rider with this seat is a huge upgrade for comfort.

 

My last seat cost me about $23,000. Thank God it came with frame, wheels, engine, wimpshield, radio, etc......Made all the difference in the world! My old metric just didn't cut it, couldn't ride for more than a couple hours. Now I can ride all day, 8-10 hours. (Oh, stock seat by the way)

 

Only Mustang's for me. I have them on both bikes.