I'm about to pick up my new to me 2012 Street Glide after having power duals, monster rounds, and the air intake put on. I plan to black my bike out and have been looking at the airstrike savage eclipse air cleaner.

If I get this would I need to take my bike back and have it retuned?

Probably asked a million times, I apologize if I missed the answer when I searched for it.

 

It's always beneficial to retune, but if you are just changing from one a/c to another you'll be fine.
Now that you've improved air flow you need the right cam for the direction you want to go in to make use of the improved breathing.

 

It is wise to get everything done before spending out on a dyno tune! You could ask your dyno man for his opinion on the filter change.